Alkyl Polyglycosides ka Lihlahisoa tsa Tlhokomelo ea Motho

Lilemong tse leshome tse fetileng, nts'etsopele ea lihlahisoa tsa lihlahisoa tsa tlhokomelo ea motho e tsoetse pele likarolong tse tharo tse kholo:

(1) bonolo le tlhokomelo ea letlalo

(2) maemo a boleng bo holimo ka ho fokotsa lihlahisoa le ho latela litšila

(3) kamano ea tikoloho.

Melao ea molao le litlhoko tsa bareki li ntse li tsoela pele ho susumetsa lintlafatso tse latelang melaoana ea ts'ebetso le ts'ebetso ea lihlahisoa. Karolo e 'ngoe ea molao-motheo ona ke tlhahiso ea alkyl glycosides ho tloha oli ea meroho le lik'habohaedreite tse tsoang mohloling o tsosolositsoeng. Nts'etsopele ea theknoloji ea khoebo e hloka taolo e phahameng ea lisebelisoa tse tala, karabelo le maemo a ts'ebetso ho fihlela litlhoko tsa boleng ba lisebelisoa tsa sejoale-joale tsa litlolo le ho li hlahisa ka theko e tlase. Lefapheng la litlolo, alkyl glucoside ke mofuta o mocha oa surfactant o nang le thepa e tloaelehileng e seng ea ionic le anionic. Ho fihlela joale, karolo e kholo ka ho fetisisa ea lihlahisoa tsa khoebo ke bahloeki ba emeloang ke C8-14 alkyl glycosides, e khetholloang ke litšobotsi tsa bona tsa letlalo le moriri. C12-14 alkyl polyglycoside e sebetsa joalo ka emulsifier mekhoeng e itseng haholo-holo ho li-microemulsions le ho ithuta ts'ebetso ea C16-18 alkyl polyglycoside e le setsi sa ho itlhahisa sa o/w se kopantsoeng le joala bo mafura.

Bakeng sa metsoako ea ho hloekisa 'mele, motho ea ncha oa sejoale-joale o tlameha ho lumellana hantle le letlalo le lera la mucous. Dermatological le toxicological liteko ho hlokahala ho hlahloba kotsi ea surfactant e ncha le moralo bohlokoa ka ho fetisisa ho hlwaya khoneha stimulation ea lisele tse phelang ka epidermal basal lera. Nakong e fetileng, sena e bile motheo oa lipolelo tse bonolo tsa surfactant. Ka nako e ts'oanang, moelelo oa bonolo o fetohile haholo.Kajeno, bonolo bo utloisisoa e le ho lumellana ka ho feletseng ha li-surfactants le physiology le mosebetsi oa letlalo la motho.

Ka mekhoa e fapaneng ea dermatological le biophysical, litlamorao tsa 'mele tsa li-surfactants letlalong li ile tsa ithutoa, ho qala ho tloha holim'a letlalo le ho fetela pele ho karolo e tebileng ea lisele tsa basal ka stratum corneum le ts'ebetso ea eona ea thibelo.Ka nako e ts'oanang, maikutlo a ikemetseng , joalo ka maikutlo a letlalo, li ngotsoe ka puo ea ho ama le phihlelo.

Alkyl polyglycosides e nang le liketane tsa alkyl tsa C8 ho isa ho C16 ke tsa sehlopha sa li-surfactants tse bonolo haholo bakeng sa ho hloekisa 'mele. Phuputsong e qaqileng, ho lumellana ha alkyl polyglycosides ho hlalositsoe e le ts'ebetso ea ketane e hloekileng ea alkyl le tekanyo ea polymerization.Tlhahlobong e fetotsoeng ea Duhring Chamber Test, C12 alkyl polyglycoside e bonts'a boholo bo lekanang ka har'a mefuta e meng ea ho teneha ha bonolo athe C8, C10 le C14, C16 alkyl polyglycoside li hlahisa lintlha tse tlase tsa ho teneha. Sena se lumellana le litebello le lihlopha tse ling tsa li-surfactants. Ho phaella moo, ho teneha ho fokotseha hanyenyane ka tekanyo e ntseng e eketseha ea polymerization (ho tloha DP = 1.2 ho DP = 1.65).

Lihlahisoa tsa APG tse nang le bolelele ba ketane ea alkyl e tsoakiloeng li lumellana hantle ka ho fetesisa le karolo e phahameng ea alkyl glycosides e telele (C12-14). Li ile tsa bapisoa ka ho eketsoa ha li-alkyl ether sulphates tse bonolo haholo, amphoteric glycine kapa amphoteric acetate, le protheine e bonolo haholo. -mafura a mafura ho collagen kapa koro proteolytic dintho.

Liphuputso tsa dermatological tekong ea ho hlatsoa letsoho la flex li bontša boemo bo tšoanang le ba Teko ea Chamber ea Duhring e fetotsoeng moo ho fuputsoang litsamaiso tse tsoakiloeng tsa alkyl ether sulfate le alkyl polyglycosides kapa li-amphoteric co-surfactants. Leha ho le joalo, tlhahlobo ea ho hlatsoa matsoho ka letsoho e lumella phapang e ntle ea liphello. Sebopeho sa erythema le squamation se ka fokotsoa ka 20-30 D/o haeba hoo e ka bang 25 °10 ea SLES e nkeloa sebaka ke alkyl polyglycoside e bontšang phokotso ea hoo e ka bang 60%. Kaho e hlophisehileng ea sebopeho, ho ka finyelloa se nepahetseng ka ho eketsoa ha li-protein kapa li-amphoteric.